Workbook for Organic Synthesis: The Disconnection Approach

Preface vii

General References ix

1. The Disconnection Approach 1

2. Basic Principles: Synthons and Reagents: Synthesis of Aromatic Compounds 5

3. Strategy I: The Order of Events 11

4. One-Group C–X Disconnections 15

5. Strategy II: Chemoselectivity 21

6. Two-Group C–X Disconnections 29

7. Strategy III: Reversal of Polarity, Cyclisations, Summary of Strategy 35

8. Amine Synthesis 41

9. Strategy IV...