Molecular Dynamics of Monomeric IAPP in Solution: A Study of IAPP in Water at the Percolation Transition

Biological activity for most living organisms is at its highest where the percolation transition occurs; hence, finding such temperature range was of utmost importance. After having found such temperature interval, i.e., between 310K and 330K, conformational studies were performed on full-length human and rat islet amyloid polypeptide, hIAPP and rIAPP respectively, by MD simulations both for the r...