Stem Cell Engineering

Preface.- Executive Summary .- Introduction.- Background .- Scope of the Study.- Prior Work at WTEC.- Panel Members.-  Study Process.- Overview of the Report.- Translational Models.- Education.-Opportunities for Collaboration.-  State of Stem Cell Engineering Outside of North America.- Conclusions.-  Physical and Engineering Principles in Stem Cell Research.- Introduction.-  Mechanoregulation of Stem Cell Function.- Topographical and Shape Features of the Stem Cell Niche.-  Electric Fields.- Mass Transfer Influences on Stem Cell Behavior.- Development of Novel Technologies to Study Stem Cells.-  Future Directions.- Global Assessment and Conclusions.- High-throughput Screening, Microfluidics, Biosensors, and Real-time Phenotyping.-  Introduction.-  High-throughput Screening of Factors Regulating Stem Cell Fates.- Global Assessment and Conclusions.- Computational Modeling and Stem Cell Engineering.- Introduction.-  Current Trends in Computational Stem Cell Engineering.- Future Opportunities.- Global Assessment and Conclusions.- Stem Cell Bioprocessing and Biomanufacturing.- Introduction.-  Stem Cell Bioprocessing Culture Technologies.-  Automation Platforms for Stem Cell Culture And Preservation.-  Future Directions.- Global Assessment and Conclusions.- Appendix A. Delegation Biographies.- Appendix B. Site Visit Reports.-  Academy of Military Medical Sciences, Tissue Engineering Research Center.- Basel Stem Cell Network (BSCN), University Hospital Basel and University of Basel.- Berlin-Brandenburg Center for Regenerative Therapies.- Chinese University of Hong Kong (CUHK).- Fraunhofer Institute for Immunology and Cell Therapy.- Fudan University, Zhongsan Hospital.- Institute for Medical Informatics and Biometry (IMB), Dresden University of Technology (TUD).-  Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I-STEM).- Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences.- Institute of Biophysics, Chinese Academy of Sciences.-  Institute of Zoology, Chinese Academy of Sciences.-  Karolinska Institute and Karolinska University Hospitals.- Keio University, Yagami Campus.-  Kyoto University-CiRA (Center for iPS Cell Research and Application).- Laboratory of Stem Cell Bioengineering (LSCB), École Polytechnique Fédérale de Lausanne (EPFL).-  Leiden University Medical Center.- Life&Brain Center, Bonn.- Lonza Cologne GmbH.- Lund University Biomedical Centre (BMC).- Max Planck Institute for Molecular Biomedicine.- National Natural Science Foundation of China (NSFC).- National Tissue Engineering Center, Shanghai Jiao Tong University School of Medicine.- Netherlands Initiative for Regenerative Medicine.- Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.- Peking University, The College of Life Sciences.-  RIKEN Institute, Kobe.- Shanghai Jiao Tong University, School of Medicine.- State Key Laboratory of Bioreactor Engineering.- Swiss Center for Regenerative Medicine (SCRM), University Hospital Zurich and University of Zurich.- Tokyo Women’s Medical University.- Tongji University School of Medicine.- Tsinghua University, School of Medicine.-  University of Tokyo, Hongo Campus, Department of Biomedical Engineering.-  University of Tokyo, Hongo Campus, Laboratory of Cell Growth and Differentiation.- University of Tokyo, Komaba Campus, Research Center for Advanced Science and Technology.-  University of Tokyo, Komaba II Campus, Institute of Industrial Science.- University of Tokyo, Shirokanedai Campus.- Uppsala University.- Appendix C. “Virtual” Site Visit Reports.-  Bioprocessing Technology Institute.- Conference for Stem Cell Engineering.-  MEDIPOST, CO., Ltd. .- National University of Singapore (NUS).- Pharmicell Co., Ltd. .- Stem Cell Bioengineering Laboratory, Instituto Superior Técnico (IST).- Instituto de Engenharia Biomédica (INEB).- Royan Institute for Stem Cell Biology and Technology (RI-SCBT).- Stem Cells Australia.-  Appendix D. Glossary of Abbreviations and Acronyms