Like many companies, PocketBook uses cookie technology to enhance your user experience, for analytics and marketing purposes that are to show you relevant offers, tailored the best to your interests while running this website and third parties websites. PocketBook respects your privacy rights, thus we kindly ask you to take a moment to enjoy Managing Cookie Preferences Please take a note that strictly necessary cookies are always enabled. If you are happy with the use of all cookie files, just click Ok in this pop-up. To learn more about cookie technology, its benefits and how Pocketbook use it, please go to our Cookie Notice
You can change your cookie settings at any time, using your cookie settings. You can use this page through your account. For more information about cookies and how we use them, please see our cookie notice.
Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health.
The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.