Learning and Memory.- Animal Models of Anxiety.- Genetic Alterations of the Murine Serotonergic Gene Pathway: The Neurodevelopmental Basis of Anxiety.- Mutagenesis and Knockout Models: Hypothalamic- Pituitary- Adrenocortical System.- Mutagenesis and Knockout Models: NK and Substance P.- Genetic Epidemiology of Anxiety Disorders.- Interactions Between Corticotropin-Releasing Hormone and Serotonin: Implications for the Aetiology and Treatment of Anxiety Disorders.- Anxiety Disorders: Noradrenergic Neurotransmission.- Pathophysiology and Pharmacology of GABAA Receptors.- Excitatory Amino Acid Neurotransmission.- Neurobiology and Treatment of Anxiety: Signal Transduction and Neuronal Plasticity.- Neuropeptides in Anxiety Modulation.-Neuroendocrine Aspects of PTSD.- Anxiety Disorders: Clinical Presentation and Epidemiology.- Transcultural Issues.- Challenge Studies in Anxiety Disorders.- Pharmacotherapy of Anxiety.- New Pharmacological Treatment Approaches for Anxiety.- Pharmaco-Genomics.- Pharmaco-Proteomics.